目的比较药物治疗与食疗对婴幼儿轻度缺铁性贫血的疗效差异,为婴幼儿轻度缺铁性贫血的治疗提供参考。方法选取2014年4月1日-2015年3月31日于湛江市赤坎区妇幼保健院儿童保健门诊首次诊断轻度缺铁性贫血且家长自愿参与本研究的837例6~36月龄的婴幼儿作为研究对象,依家长意愿分为治疗组(药物治疗)与对照组(食疗)两组,于治疗1个月、3个月后(7天内)采末梢血行血细胞分析,比较两组患儿的贫血治疗有效率和血红蛋白浓度(HGB/Hb)、平均红细胞容积(MCV)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)水平差异。结果治疗1个月后,治疗组有效率(74.13%)和HGB水平(112.59±4.45)g/L明显高于对照组有效率(14.71%)和HGB水平(105.36±4.38)g/L,差异均有统计学意义(χ²=300.50,P<0.01;t=23.688,P<0.01)。治疗3个月后,治疗组有效率(92.79%)和HGB水平(120.71±5.17)g/L明显高于对照组有效率(59.54%)和HGB水平(109.87±2.81)g/L,差异均有统计学意义(χ²=124.90,P<0.01;t=31.438,P<0.01);治疗组治疗3个月后有效率(92.79%)和HGB水平(120.71±5.17)g/L明显高于治疗1个月后有效率(74.13%)和HGB水平(112.59±4.45)g/L,差异均有统计学意义(χ²=55.313,P<0.01;t=51.121,P<0.01)。结论婴幼儿轻度缺铁性贫血的治疗需以药物治疗为主,食疗为辅,治疗应坚持足够疗程,在Hb值恢复正常后仍需继续补充铁剂2个月,以恢复机体铁储备水平。

Objective Comparing the difference of the curative effects of drug therapy and dietary therapy on mild iron deficiency anemia,in order to provide reference for the treatment of mild iron deficiency anemia in infants. Methods From April 1,2014 to March 31,2015,837 infants aged 6-months to 3-years who were found mild iron deficiency anemia for the first time in Maternal and Child Care Hospital of Chikan District in Zhanjiang city were enrolled in this study,and their parents were volunteered to participate in this study. All subjects were divided into the treatment group( drug therapy group) and the control group( dietary therapy group) in accordance with the parents ' will. All subjects were tested blood in 1 month,3 months after treatment( within 7 days). The differences of the treatment effective rates,the levels of hemoglobin concentration( HGB),the mean corpuscular volume( MCV),the mean corpuscular hemoglobin( MCH) and the mean corpuscular hemoglobin concentration( MCHC) were compared between the two groups. Results After 1 month of therapy,compared with control group,treatment group had higher treatment effective rate( 74. 13%vs. 14. 71%) and HGB level [( 112. 59 ± 4. 45 vs. 105. 36 ± 4. 38) g / L],the differences was statistically significant respectively( χ²= 300. 50,P < 0. 01; t = 23. 688,P < 0. 01); After 3 month of therapy,treatment group had higher treatment effective rate( 92. 79% vs. 59. 54%) and HGB level [( 120. 71 ± 5. 17 vs. 109. 87 ± 2. 81) g/L]than those of control group,the differences was statistically significant respectively( χ²= 124. 90,P < 0. 01; t = 31. 438,P < 0. 01); The treatment effective rate and HGB level after3 months of therapy were significantly higher than those after 1 month of therapy in treatment group,the differences was statistically significant respectively( χ²= 55. 313,P < 0. 01; t = 51. 121,P < 0. 01). Conclusion The main therapy of the mild iron deficiency anemia in infants should be pharmacotherapy,supplemented by dietary therapy,and the treatment should adhere adequate course of treatment. To restore the body's iron reserves level,iron still need be supplemented for 2 months after the HGB returned to normal.