目的分析贵阳市HIV感染孕产妇的感染状况,药物干预情况,了解预防艾滋病母婴传播项目的服务现况,分析存在的困难和原因,探索解决的方法,为贵阳市制定相关的服务策略提供依据,促进规范执行预防艾滋病母婴传播项目,切实减少艾滋病母婴传播。方法对贵阳市2011-2014年上报到全国预防艾滋病、梅毒和乙肝母婴传播管理信息系统中的HIV感染孕产妇及其所生儿童的个案资料进行回顾性分析。结果 HIV阳性孕产妇文化程度较低,70.1%为初中及以下;仅产时检测阳性者比例较大,占34.4%;产妇服药率67.2%,其中仅产时阳性产妇服药率为19%;新生儿用药干预率为81.2%,新生儿人工喂养率96.7%。结论贵阳市HIV感染产妇用药干预率未达目标要求(80%),主要原因是仅产时筛查阳性孕产妇服药率低。孕产妇在孕前和孕期及早确诊HIV,提高医务人员的咨询技能,有利于提高抗病毒药物应用的依从性,降低母婴传播率。

Objective To analyze the infectious status and antiretroviral( ARV) drugs intervention of HIV-infected pregnant women in Guiyang,in order to understand current situation and problems of the prevention of mother-to-child transmission of HIV( PMTCT) services,and to provides evidence for making further adjustments and specific strategies. Methods Retrospective analyzed the HIV-infected pregnant women and their infants based on the data from management information system of i PMTCT program that reported form Guiyang from 2011 to 2014. Results The educational level of 70. 1% HIV-positive pregnant women was under primary school. The proportion of HIV-positive pregnant women who were detected at delivery time was 34. 4%. 67. 2% were received ARVs for PMTCT and 19% of them received ARVs at delivery time. ARVs intervention rate of newborn was 81. 2%. Formula feeding rate of newborn was 96. 7%. Conclusion The ARVs intervention rate in Guiyang was less than 80% and didn't achieve the target which was 80% because of the relatively low drug intervention rate at delivery time. Early diagnosis of HIV at per-pregnancy and pregnancy,and improving the consulting skill of medical technician can raise patient's willingness for using ARVs and reduce the rate of motherinfant transmission.