目的了解福安市妊娠梅毒发病率,探讨妊娠梅毒筛查、治疗与不良妊娠结局,评价开展预防梅毒母婴传播工作的意义。方法按国家《预防艾滋病、梅毒和乙肝母婴传播工作实施方案》开展预防梅毒母婴传播工作,收集分析2011年12月-2014年3月福安全市分娩产妇的梅毒筛查状况。结果 2011年12月-2014年3月该市有分娩产妇26 818名,其中进行孕期梅毒筛查的孕产妇24 654名,梅毒筛查率91.93%。检出梅毒感染孕产妇409例(334例已结束妊娠、75例尚未分娩),均为隐性梅毒,隐性梅毒占100%,妊娠梅毒发病率16.59‰(409/24 654)。334例已结束妊娠的梅毒感染孕产妇正常妊娠结局316例(占94.61%),不良妊娠结局18例(占5.39%)。规范治疗183例,其正常妊娠结局100%,不良妊娠结局0%;未规范治疗151例,其正常妊娠结局88.08%,不良妊娠结局11.92%。结论开展孕期梅毒筛查,及早发现、及时规范治疗,对预防梅毒母婴传播,改善不良妊娠结局具有重大意义。

Objective To analysis the incidence rate of pregnant syphilis in Fuan city.We discussed the screening,treatment and adverse pregnancy outcomes of pregnant syphilis and evaluated the significance of prevent the mother-to-child transmission of syphilis.Methods According to the country " t Wheork plan of prevention of mother-to-child transmission of HIV,syphilis and hepatitis Bb ",we analyzed the data collected from onsyphilis screening among pregnant women who was in labor in all hospitals of Fuan from 2011 December to 2014 March.Results There totally 26 818 pregnant women were collected as objects,24 654 of them accepted the syphilis screening,and the syphilis screening rate was 91.93%.409 pregnant were infected by syphilis,were all infected by the stealth viruses,the rate of incidence was 16.59‰( 409 /24 654).334 pregnant of them have finished the pregnancy and 75 pregnant terminated gestation.316 pregnant were the normal pregnancy outcome among the 409 affected pregnant,and the incidence of adverse pregnancy outcome was 5.39%( 18 /334).183 cases were accepted standard treatment and 151 cases were not accepted the standard treatment.The incidence rate of adverse pregnancy outcome between the two groups was 0% and 11.92% respectively.Conclusions To carry out prenatal syphilis screening,early detection,timely standardized treatment,is of great significance to prevent syphilis mother-to-child transmission and improve the adverse pregnancy outcome.