目的对两种宫颈癌筛查方案进行效果评价,为决策提供依据。方法通过对筛查早诊率、检出率、发现早期病例平均费用、早期发现成本系数(early detection cost index,EDCI)几个指标的对比分析,评价两种宫颈癌筛查方法。结果总体上看,采用"HPV检测方案"初筛检出率(1.83%)高于"延续宫颈癌方案"初筛检出率(0.59%),差异有统计学意义(P=0.000),两种筛查方案在筛查早诊率方面的差异无统计学意义(P=0.089)。"HPV检测方案"早期病例平均费用、早期发现成本系数均低于"延续宫颈癌方案"。结论从"用更小的成本筛查出更多的癌症早期患者"的角度出发,"HPV检测方案"优于"延续宫颈癌筛查方案"。

Objective To evaluate the effect of two types of cervical cancer screening programs and provide basis for decisionmaking.Method Through the comparative analysis of early diagnosis rate, detection rate, average cost of early case detection and early detection cost index(EDCI), two types of cervical cancer screening program were evaluated.Result In general, the primary screening rate of "HPV test screening program"(1.83%) was higher than that of "Cytological test screening program"(0.59%),P= 0. 000. There was no significant difference in the early diagnosis rate between the two screening programs(P= 0. 089). The average cost of early cases and the cost coefficient of early detection in the "HPV test screening program" were lower than that in the "Cytological test screening program ".Conclusion From the perspective of " screening more early cancer patients at a lower cost," the " HPV test screening program " is better than the " Cytological test screening program. "