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目的观察早产儿对复方托吡卡胺散瞳滴眼液的药物反应。方法随机选取2014年12月-2015年6月广东省妇幼保健院新生儿监护室(NICU)出生体重≤1501 g或出生胎龄≤32周的早产儿。随机选取50名患儿,左眼点复方托吡卡胺滴眼液,5 min 1次,共2次;右眼点复方托吡卡胺滴眼液,5 min 1次,共3次。观察不同点眼次数,瞳孔散大的效果。随机选取50名早产儿使用散瞳滴眼液,5 min 1次,共3次,使用早产儿疼痛量表(PIPP)计分方法进行疼痛指数计分(PIPP分值)。结果1复方托吡卡胺滴眼液,30 min时左眼的瞳孔大小<右眼,差异有统计学意义(P<0.01);2患儿对散瞳滴眼液有明显的疼痛反应;PIPP值(7.41±0.53)。结论 1早产儿使用复方托吡卡胺散瞳,需要点眼3次才能达到理想的散瞳效果;2散瞳药会对早产儿造成中等程度的疼痛刺激。
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基本信息:
DOI：10.19757/j.cnki.issn1674-7763.2016.03.026
中图分类号:R774.1
引用信息:
[1]孙伟,李静,黄学林等.早产儿对复方托吡卡胺散瞳滴眼液的药物反应[J].中国妇幼卫生杂志,2016,7(03):88-90.DOI:10.19757/j.cnki.issn1674-7763.2016.03.026.
基金信息: