目的分析在临床安全输血中孕妇与非孕妇受血者不规则抗体筛查的临床价值。方法 2017年3月-2019年3月收入深圳市福田区妇幼保健院的120例申请输血女性患者,依据是否怀孕将其分为非孕妇组(n=70例)和孕妇组(n=50例),开展受血者不规则抗体筛查、不规则抗体筛查特异性分布情况,并分析孕妇与非孕妇受血者不规则抗体筛查阳性率。结果 120例受血者不规则抗体总筛查率是29. 16%,其中抗-M占5. 83%,抗-D占5. 00%,抗-E占4. 16%,抗-C占3. 33%,抗-PI占2. 50%,抗-Leb占1. 67%,抗-Lea占1. 67%,抗-H占0. 83%,抗-H占0. 83%,抗-Fyb占0. 83%,抗-N占0. 83%,抗-JKa占0. 83%;非特异性抗体占1. 67%。非孕妇组受血者不规则抗体筛查阳性率21. 42%,低于孕妇组阳性率(40. 00%),差异有统计学意义(P <0. 05)。结论在对女性患者,尤其是孕妇,在输血前有必要实施受血者不规则抗体筛查,明确不规则抗体筛查特异性分布情况,有利于确保输血的整体安全性。

Objective To analyze and study the clinical value of screening for irregular antibodies in pregnant and non-pregnant women receiving blood transfusions. Methods This study was conducted in 120 women who were admitted to our hospital from March2017 to March 2019. They were divided into non-pregnant women( n = 70 cases) and pregnant women( n = 50 cases) depending on whether they were pregnant. The irregular antibody screening and the specific distribution of irregular antibody screening in blood recipients were carried out,and the positive rate of irregular antibody screening in pregnant and non-pregnant women was analyzed.Results The total screening rate of irregular antibodies in 120 recipients was 29. 16%,of which anti-M occupied 5. 83%,anti-D occupied 5. 00%,anti-E occupied 4. 16%,anti-C occupied 3. 33%,Aanti-PI occupation ratio 2. 50%,anti-Leb occupancy ratio1. 67%,anti-Lea occupation ratio 1. 67%,anti-H occupation ratio 0. 83%,anti-H occupation ratio 0. 83%,anti-Fyb occupation ratio0. 83%,-N occupied 0. 83%,anti-JKa occupied 0. 83%,and non-specific antibody occupied 1. 67%. The positive rate of irregular antibody screening in non-pregnant women was 21. 42%,which was lower than that in pregnant women( 40. 00%),and the difference was statistically significant( P < 0. 05). Conclusion Before carrying out blood transfusion for female patients,especially pregnant women,it is necessary to carry out screening of irregular antibodies in recipients,in order to ensure the overall blood transfusion safety.